Application status of veterinary antibiotics and substitution potential of probiotics


Published on:

2022-03-25

Antibiotics are widely abused. At present, most of the diseases in livestock and poultry ....

Application status of veterinary antibiotics and substitution potential of probiotics
Antibiotics are widely abused. At present, most of the diseases in livestock and poultry breeding and aquaculture are caused by mixed infection of bacteria and viruses under normal or stress, and antibiotic treatment is still the first choice. In order to improve production efficiency, many farmers add a lot of antibiotics in the breeding process, so as to prevent and control diseases. In reality, the blind use of antibiotics not only increases the difficulty of epidemic prevention and control, but also increases the treatment cost, which has affected the export of livestock products to varying degrees, and finally caused the loss of economic benefits.
Some veterinary antibiotics have caused different negative effects on animal health. The doses of metronidazole reported by veterinarians from 2017 to 2004 were lower than those of metronidazole in 26 dogs diagnosed as neurotoxicity by Tauro et al. It is speculated that with the extensive application of antibiotics, some drugs can cause serious adverse reactions in animals even in a small dose. Other studies have shown that the use of antibiotics can change the intestinal microecological balance, resulting in antibiotic associated diarrhea (AAD) and other diseases.
The use of antibiotics may promote the production of antibiotic resistant bacteria. At present, the development of antibiotics lags far behind the evolution rate of drug-resistant bacteria. The emergence of drug-resistant superbacteria and the lack of new antibiotics to treat human and animal diseases have become a global problem. Umedak et al. Screened the presence of drug-resistant bacteria from 151 dogs and 182 cats by collecting fecal samples or rectal swabs. This study found that there were several types of cephalosporin resistant Enterobacteriaceae in companion animals.

 

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